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Sunday, October 17 |
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7:30 am - 9:00 am |
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- WORKSHOP 1 Room A |
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Bioimaging technology and evaluation protocols for skeletal research
Co-Organizers: Ling QIN, PhD, Hong Kong, China and Gang LI, MD, PhD, Hong Kong, China
Chinese Orthopaedic Research Society
To provide a perspective on the current statues of bioimaging technologies developed for assessment of quality of musculoskeletal tissues with emphasis on bone and cartilage, evaluations of scaffold biomaterials developed for enhancement of repair of musculoskeletal tissues.
To provide a unique platform for multidisciplinary collaborations in education and joint R&D among various professions, including biomedical engineering, biomaterials, and basic and clinical medicine.
MicroCT for skeletal and non-skeletal applications
Speaker: Ling QIN, PhD, Hong Kong, China
Quantitative Assessment of Osteoporotic Fracture Repair
Speaker: Gang LI, MD, PhD, Hong Kong, China |
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- WORKSHOP 2 Room D |
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Updates on the Biological Repair of intervertebral discs
Organizer: John Antoniou, MD, PhD, FRCSC, Montreal, QC, Canada
Canadian Orthopaedic Research Society
Degenerative disc disease begins in the central nucleus pulposus region and is implicated as a major component of spine pathology. Currently, the two major clinical procedures for treating disc degeneration are disc excision and spinal fusion. Although these procedures offer relatively good short-term clinical results in relief of pain, in many instances they are disappointing because of altered spinal mechanics that leads to subsequent degeneration at adjacent disc levels. Biological repair of the degenerate disc would be the ideal treatment and recent advances in tissue engineering offer the unique opportunity to repair, or at least retard, further degeneration of the nucleus pulposus using growth factor supplementation and mesenchymal stem cells.
The purpose of this workshop will be to discuss the value and limitations of current surgical techniques for treating disc degeneration and the feasibility of biological repair being a reality in the future.
What causes disc degeneration and can it be repaired
Speaker: Fackson Mwale, PhD, Montreal, QC, Canada
Growth factor therapy for intervertebral disc repair
Speaker: Koichi Masuda, MD, San Diego, CA, USA
Cell-mediated therapy for intervertebral disc repair
Speaker: Daisuke Sakai, MD, PhD, Kanagawa, Japan |
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- WORKSHOP 3 Room E |
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New tools for routine clinical outcome assessment: From changing patient demands to improved questionnaires, motion analysis and activity monitoring
Organizer: Bernd Grimm, PhD, MEng, Heerlen, the Netherlands
European Orthopaedic Research Society
As arthroplasty patients are getting younger and the older ones lead more active lifestyles, rising functional demands join pain relief as an increasingly relevant dimension of outcome and satisfaction. This exceeds the capacity of classic questionnaires conceived for the first generation of arthroplasty patients. Thus today these questionnaires suffer from a ceiling effect, subjectivity and pain dominance masking functional changes. As a consequence clinical studies increasingly fail to demonstrate differences between treatment options stifling or misdirecting therapeutic innovation. New outcome measures for routine clinical follow-up are required to provide orthopaedics with the evidence base for therapeutic advances.
The purpose of this workshop is to describe the ongoing changes in patient demands and its consequences for the use of questionnaires in follow-up studies. Three advanced methods of outcome assessment are explained and evaluated: 1.) New, improved questionnaires which remove the ceiling effect and raise the weight of functional changes 2.) inertia-sensor based motion analysis as a simple and clinically feasible alternative to lab-based motion analysis and 3.) activity monitoring to observe true function and usage in the free field versus the outpatient visit only.
Changing patient demands and the status of questionnaire based outcome assessment
Speaker: Ashley Blom, MD, PhD, Bristol, United Kingdom
New questionnaire based outcome scores for research and clinical follow-up
Speaker: Phil Noble, PhD , Houston, TX, USA
Inertia-sensor based motion analysis and activity monitoring in routine clinical follow-up
Speaker: Bernd Grimm, PhD, MEng, Heerlen, the Netherlands |
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Tuesday, October 19 |
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7:30 am- 9:00 am |
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- WORKSHOP 4 Room A |
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Advances in musculoskeletal tissue engineering
Co-Organizers: Gun-Il Im, MD, Goyang, Korea and Soon-Yong Kwon, Dong, Korea
Korean Orthopaedie Research Society
Musculoskeletal system has been one of prime foci for tissue engineeing approach. In this workshop, fresh attempts for the regeneration of bone and cartilage will be introduced by three distinguished researchers in this field.
Synovial stem cell-based regeneration of tissues in the knee joint
Speaker: Ichiro Sekiya, MD, Tokyo, Japan
Sustained delivery of BMP-2 for bone and cartilage regeneration
Speaker: Byung-Soo Kim, PhD, Seoul, Korea
Ceramic -Cell Composite for Bone Regeneration in Large Osteonecrotic Lesion of the Femoral Head : Minimum 5-year Clinical Trial
Speaker: Shin-Yoon Kim, MD, Daegu, Korea |
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- WORKSHOP 5 Room D |
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Regenerative Medicine in Orthopaedic Surgery
Organizer: Johnny Huard, PhD, Pittsburgh, PA, USA
Orthopaedic Research Society (USA)
The purpose of this study is to discuss about our future direction of cartilage repair for large cartilage defects successfully with less invasive technique.
Regenerative Medicine in Orthopaedic Surgery
Speaker: Johnny Huard, PhD, Pittsburgh, PA, USA
Cartilage Repair with Cell Delivery Using Magnetic Field and Distraction
Speaker: Mitsuo Ochi, MD, PhD, Hiroshima, Japan
Updates of basic research on cartilage regeneration
Speaker: Ryosuke Kuroda, MD, PhD, Kobe, Japan |
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- WORKSHOP 6 Room E |
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Status and issue of tissue grafting in Asia
Co-Organizers: Moritoshi Itoman, MD, Fukuoka, Japan and Seiya Jingushi, MD, Fukuoka, Japan
Japanese Orthopaedic Association
The system of tissue bank and status of its infrastructure development in Asian orthopaedic field are different in Asian countries. In this workshop, three speakers from Korea and Japan review the status of tissue grafting in each country and discuss about the present issue for tissue grafting in Asia. The speakers also present their basic research performed for tissue grafting. Exchange of opinions about their researches will enable us to find an opportunity for international collaboration.
Current status of tissue banking in Japan
Speaker: Ken Urabe, MD, Kanagawa, Japan
Current status of tissue banking in Korea
Speaker: Yong-Koo Kang, MD, Kyounggi-do, Korea |
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Wednesday, October 20 |
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7:30 am - 9:00 am |
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- WORKSHOP 7 Room A |
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Biomechanical and Biomaterial Research in Percutaneous Kyphoplasty (PKP)
Co-Organizers: Huilin Yang, MD, PhD, Suzhou, China and Zong-Ping Luo, PhD, Suzhou, China
Chinese Orthopaedic Research Society
Vertebral compression fractures are common spinal disorders resulting from osteoporosis affecting 60% people over the age of 60. Percutaneous kyphoplasty (PKP), due to its minimal invasive feature, has become a popular technique in the treatment of fractures and nonunion. However, their pitfalls have also been observed. The purpose of this workshop is to update recent progress in the biomechanical and biomaterial research ans well as clinical practices in PKP, and to provide suggestions in improvement of PKP from the aspects of material strength, compatibility, biodegradation, and mechanical stability.
Percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture nonunion
Speaker: Huilin Yang, MD, Suzhou, China
Biomechanical analysis in percutaneous kyphoplasty
Speaker: Zong-Ping Luo, PhD, Suzhou, China
Recent advances in materials for percutaneous kyphoplasty
Speaker: Bin Li, PhD, Suzhou, China |
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- WORKSHOP 8 Room D |
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The prospects of the molecular targeted therapy for sarcoma
Co-Organizers: Kazuyuki Itoh, Osaka, Japan and Takatoshi Ohno, Gifu, Japan
Japanese Orthopaedic Association
In the past decade, advances on molecular targeted therapy for some kinds of cancer has brought about improvement of survival and quality of life of the patients. Some clinical trials of molecular targeted agents for sarcoma patients are now going on in Japan and we are expecting the results of the studies.
In various kinds of sarcomas, the expression of unique chimeric fusion genes, such as SYT/SSX in synovial sarcoma or EWS/Fli1 in Ewing's sarcoma, which involve the tumorigenicity has been found to date. In this workshop, we discuss the prospects of molecular targeted therapy for sarcoma which has characteristics of the fusion genes.
Synovial sarcoma is a stem cell malignancy
Speaker: Norifumi Naka, MD, PhD, Osaka, Japan
Molecular targeting of EWS-fusion genes in Ewing's sarcoma
Speaker: Takatoshi Ohno, Gifu, Japan
Immunotherapeutic targeting of fusion genes in synovial sarcoma
Speaker: Satoshi Kawaguchi, MD, PhD, Sapporo, Japan |
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